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KMID : 0613820140240111258
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Journal of Life Science
2014 Volume.24 No. 11 p.1258 ~ p.1267
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Development of an Economic-trait Genetic Marker by Applying Next-generation Sequencing Technologies in a Whole Genome
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Gim Jeong-An
Kim Heui-Soo
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Abstract
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Developing economic traits with a high growth rate, robustness, and disease resistance in livestock is an important challenge. RFLP and AFLP are the classical methods used to develop economic traits. Whole-genome-based economic traits have recently been detected with the advent of next-generation sequencing (NGS) technologies. However, NGS technologies are rather costly for use in studies, and RNA-seq, RAD-Seq, RRL, MSG, and GBS have been used to overcome the issue of high costs. In this study, recent NGS-based studies were reviewed, particularly those that focused on minimum costs and maximum effects. Then, we presented further prospects on how to apply for selection of high economic-trait livestock.
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KEYWORD
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Genetic marker, NGS technologies, restriction enzyme, whole genome
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